8 Expert Tips for Excellent Designed Experiments (DOE)

If your work involves quality improvement, you've at least heard of Design of Experiments (DOE). You probably know it's the most efficient way to optimize and improve your process. But many of us find DOE intimidating, especially if it's not a tool we use often. How do you select an appropriate design, and ensure you've got the right number of factors and levels? And after you've gathered your data, how do you pick the right model for your analysis?

gaugeOne way to get started with DOE is the Assistant in Minitab Statistical Software. When you have many factors to evaluate, the Assistant will walk you through a DOE to identify which factors matter the most (screening designs). Then the Assistant can guide you through a designed experiment to fine-tune the important factors for maximum impact (optimization designs)

If you're comfortable enough to skip the Assistant, but still have some questions about whether you're approaching your DOE the right way, consider the following tips from Minitab's technical trainers. These veterans have done a host of designed experiments, both while working with Minitab customers and in their careers in before they became Minitab trainers. 

1. Identify the right variable space to study with exploratory runs.

Performing exploratory runs before doing the main experiment can help you identify the settings of your process as performance moves from good to bad. This can help you determine the variable space to conduct your experiment that will yield the most beneficial results.                                             

2. Spread control runs throughout the experiment to measure process stability.

Since center-point runs are usually near-normal operating conditions, they can act as a control to check process performance. By spacing center points evenly through the design, these observations serve as an indicator of the stability of your process—or lack thereof—during the experiment.   

3. Identify the biggest problems with Pareto analysis.

A Pareto chart of product load or defect levels can help you identify which problem to fix that will result in the highest return to your business. Focusing on problems with high business impact improves support for your experiment by raising its priority among all potential improvement projects.
Pareto Chart of the Effects

4. Improve power by expanding the range of input settings.

Test the largest range of input variable settings that is physically possible. Even if you think they are far away from the “sweet spot,” this technique will allow you to use the experiment to understand your process so that you can find the optimal settings.

Maximizing your variable space can help you discover new insights about your process.

5. Fractionate to save runs, focusing on Resolution V designs.

In many cases, it's beneficial to choose a design with ½ or ¼ of the runs of a full factorial. Even though effects could be confounded or confused with each other, Resolution V designs minimize the impact of this confounding which allows you to estimate all main effects and two-way interactions. Conducting fewer runs can save money and keep experiment costs low.

Choosing the right fractional factorial helps reduce the size of your experiment while minimizing the level of confounding of effects.

6. Improve the power of your experiment with replicates.

Power is the probability of detecting an effect on the response, if that effect exists. The number of replicates affects your experiment's power. To increase the chance that you will be successful identifying the inputs that affect your response, add replicates to your experiment to increase its power.

Power is a function of the number of replicates.

7. Improve power by using quantitative measures for your response.

Reducing defects is the primary goal of most experiments, so it makes sense that defect counts are often used as a response. But defect counts are a very expensive and unresponsive output to measure. Instead, try measuring a quantitative indicator related to your defect level. Doing this can decrease your sample size dramatically and improve the power of your experiment.  

8. Study all variables of interest and all key responses.

Factorial designs let you take a comprehensive approach to studying all potential input variables. Removing a factor from the experiment slashes your chance of determining its importance to zero. With the tools available in statistical software such as Minitab to help, you shouldn't let fear of complexity cause you to omit potentially important input variables. 

Do you have any DOE tips to add to this list?


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